Dietary Supplement Supports Urinary Tract Health Imbalances of the urinary tract are widespread, and it is estimated that 20 percent of women will experience them. Source Naturals D-Mannose supports the health of the entire urinary tract: the urethra, bladder, ureter, renal pelvis and the renal parenchyma. D-Mannose is a monosaccharide hexose sugar, naturally found in some trees, berries and fruits, such as cranberry. It complements the body's natural cleansing process.