Standardized Extract Supports Liver and Cholesterol Metabolism Dietary Supplement Artichoke 500 Extract is standardized to contain 5% total caffeoylquinic acids. Clinical research has documented the following beneficial properties of artichoke extract: Liver Function — Protects glutathione levels. Stimulates liver activity by promoting circulation within the liver. Cardiovascular Function — Inhibits oxidation of LDL cholesterol and increases healthful levels of HDL (protective) cholesterol. Digestion — Stimulates synthesis of bile, a product of the liver that supports detoxification and the absorption of fat-soluble nutrients.