Dietary Supplement Promotes Join Comfort and Flexibility Knee & Joint Formula Contains NEM (Natural Eggshell Membrane) and Glucosamine Sulfate. NEM, made by a patented process, is clinically proven to promote joint comfort and flexibility in just 7 to 10 day. Composed of naturally occurring glycosaminoglycans including chondroitin and hyaluronic acid, NEM also contains collagen and other beneficial proteins. All Natural Factors products are manufactured in accordance with the Government of Canada's Good Manufacturing Practices (GMP), among the highest standards in the world.