SystemiCare BioAlign Supports Healthy Inflammation Response Dietary Supplement Inflama-Rest is a Bio-Aligned formula which may ease joint function and support comfortable movement via inhibition of the COX-2 enzyme. It also addresses additional factors shown in scientific research to influence muscle and joint comfort: nuclear factor-kappa B activity, leukotriene regulation and nitric oxide production. Inflama-Rest helps protect cells from free radical damage and is specially formulated with adaptogenic herbs and minerals which may help reduce muscle tension associated with physical and emotional stress.